Fields »
ABOUT
HELP
BLOG
CAMK2B

GENERAL INFORMATION

Gene name

 CAMK2B

Gene description

 Calcium/calmodulin-dependent protein kinase II beta

Protein class

 Enzymes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 15
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (cerebral cortex)
GTEx:Tissue enhanced (cerebellum)
FANTOM5:Tissue enhanced (cerebellum, caudate)

Protein evidence

 Evidence at protein level

Protein expression

 Expression in CNS, heart and skeletal muscle.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data. Caution, targets protein from more than one gene.

Reliability score

 Supported based on 5 antibodies.
HPA026307 , HPA051783 , HPA051785 , HPA053973 , CAB006849
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical
Cerebral cortexHippocampusCaudateCerebellumThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleNasopharynxBronchusLungLiverGallbladderPancreasOral mucosaSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSoft tissueSkinNotdetectedLowMediumHighSCORE

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebral cortex)
Cerebral cortexThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleLungLiverGallbladderPancreasSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSkin050100150200250TPM
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebellum)
HypothalamusPituitary glandCerebral cortexHippocampusCaudateCerebellumThyroid glandAdrenal glandSpleenHeart muscleSkeletal muscleLungLiverPancreasSalivary glandEsophagusStomachSmall intestineColonKidneyUrinary bladderTestisProstateBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryAdipose tissueSkin020406080100120RPKM
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebellum, caudate)
Pituitary glandBrainHippocampusCaudateCerebellumThyroid glandAppendixLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleLungLiverGallbladderPancreasSalivary glandEsophagusSmall intestineColonKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastVaginaCervix, uterineEndometriumOvaryPlacentaAdipose tissueRetina050100150200250300350Tags Per Million

GENE INFORMATION

Gene name

 CAMK2B (HGNC Symbol)

Synonyms

 CAM2, CAMK2, CAMKB

Description

 Calcium/calmodulin-dependent protein kinase II beta (HGNC Symbol)

Entrez gene summary

 The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Chromosome

 7

Cytoband

 p13

Chromosome location (bp)

 44217150 - 44334577

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000058404 (version 83.38)

Entrez gene

 816

UniProt

 Q13554 (UniProt - Evidence at protein level)

neXtProt

 NX_Q13554

Antibodypedia

 CAMK2B antibodies

PROTEIN BROWSER
«
CAMK2B-001
CAMK2B-002
CAMK2B-003
CAMK2B-004
CAMK2B-005
CAMK2B-006
CAMK2B-007
CAMK2B-008
CAMK2B-015
CAMK2B-016
CAMK2B-020
CAMK2B-021
CAMK2B-022
CAMK2B-026
CAMK2B-201
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CAMK2B-001
ENSP00000397937
ENST00000440254
Q13554 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0003779 [actin binding]
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007268 [synaptic transmission]
GO:0007411 [axon guidance]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010976 [positive regulation of neuron projection development]
GO:0014733 [regulation of skeletal muscle adaptation]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0030666 [endocytic vesicle membrane]
GO:0033017 [sarcoplasmic reticulum membrane]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042803 [protein homodimerization activity]
GO:0045087 [innate immune response]
GO:0046777 [protein autophosphorylation]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048169 [regulation of long-term neuronal synaptic plasticity]
GO:0051823 [regulation of synapse structural plasticity]
GO:0051924 [regulation of calcium ion transport]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:0060998 [regulation of dendritic spine development]
GO:0061003 [positive regulation of dendritic spine morphogenesis]
GO:0090129 [positive regulation of synapse maturation]
GO:1900034 [regulation of cellular response to heat]
Show all
 542 aa
60.4 kDa 		No 1
CAMK2B-002
ENSP00000379098
ENST00000395749
Q13554 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit beta
A4D2J9 [Target identity:100%; Query identity:100%]
Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000082 [G1/S transition of mitotic cell cycle]
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0002030 [inhibitory G-protein coupled receptor phosphorylation]
GO:0003779 [actin binding]
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0006816 [calcium ion transport]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007268 [synaptic transmission]
GO:0007411 [axon guidance]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010976 [positive regulation of neuron projection development]
GO:0014069 [postsynaptic density]
GO:0014733 [regulation of skeletal muscle adaptation]
GO:0018105 [peptidyl-serine phosphorylation]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0019901 [protein kinase binding]
GO:0030425 [dendrite]
GO:0030666 [endocytic vesicle membrane]
GO:0032222 [regulation of synaptic transmission, cholinergic]
GO:0032430 [positive regulation of phospholipase A2 activity]
GO:0033017 [sarcoplasmic reticulum membrane]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042803 [protein homodimerization activity]
GO:0043204 [perikaryon]
GO:0043274 [phospholipase binding]
GO:0045087 [innate immune response]
GO:0046686 [response to cadmium ion]
GO:0046777 [protein autophosphorylation]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048169 [regulation of long-term neuronal synaptic plasticity]
GO:0048858 [cell projection morphogenesis]
GO:0050885 [neuromuscular process controlling balance]
GO:0051233 [spindle midzone]
GO:0051823 [regulation of synapse structural plasticity]
GO:0051924 [regulation of calcium ion transport]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:0060466 [activation of meiosis involved in egg activation]
GO:0060998 [regulation of dendritic spine development]
GO:0061003 [positive regulation of dendritic spine morphogenesis]
GO:0090129 [positive regulation of synapse maturation]
GO:0097481 [neuronal postsynaptic density]
GO:1900034 [regulation of cellular response to heat]
GO:2001235 [positive regulation of apoptotic signaling pathway]
Show all
 666 aa
72.7 kDa 		No 1
CAMK2B-003
ENSP00000379096
ENST00000395747
Q13554 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0003779 [actin binding]
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007268 [synaptic transmission]
GO:0007411 [axon guidance]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010976 [positive regulation of neuron projection development]
GO:0014733 [regulation of skeletal muscle adaptation]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0030666 [endocytic vesicle membrane]
GO:0033017 [sarcoplasmic reticulum membrane]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042803 [protein homodimerization activity]
GO:0045087 [innate immune response]
GO:0046777 [protein autophosphorylation]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048169 [regulation of long-term neuronal synaptic plasticity]
GO:0051823 [regulation of synapse structural plasticity]
GO:0051924 [regulation of calcium ion transport]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:0060998 [regulation of dendritic spine development]
GO:0061003 [positive regulation of dendritic spine morphogenesis]
GO:0090129 [positive regulation of synapse maturation]
GO:1900034 [regulation of cellular response to heat]
Show all
 518 aa
58 kDa 		No 1
CAMK2B-004
ENSP00000351542
ENST00000358707
Q13554 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0003779 [actin binding]
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007268 [synaptic transmission]
GO:0007411 [axon guidance]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010976 [positive regulation of neuron projection development]
GO:0014733 [regulation of skeletal muscle adaptation]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0030666 [endocytic vesicle membrane]
GO:0033017 [sarcoplasmic reticulum membrane]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042803 [protein homodimerization activity]
GO:0045087 [innate immune response]
GO:0046777 [protein autophosphorylation]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048169 [regulation of long-term neuronal synaptic plasticity]
GO:0051823 [regulation of synapse structural plasticity]
GO:0051924 [regulation of calcium ion transport]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:0060998 [regulation of dendritic spine development]
GO:0061003 [positive regulation of dendritic spine morphogenesis]
GO:0090129 [positive regulation of synapse maturation]
GO:1900034 [regulation of cellular response to heat]
Show all
 503 aa
56.4 kDa 		No 1
CAMK2B-005
ENSP00000326544
ENST00000347193
Q13554 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0003779 [actin binding]
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007268 [synaptic transmission]
GO:0007411 [axon guidance]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010976 [positive regulation of neuron projection development]
GO:0014733 [regulation of skeletal muscle adaptation]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0030666 [endocytic vesicle membrane]
GO:0033017 [sarcoplasmic reticulum membrane]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042803 [protein homodimerization activity]
GO:0045087 [innate immune response]
GO:0046777 [protein autophosphorylation]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048169 [regulation of long-term neuronal synaptic plasticity]
GO:0051823 [regulation of synapse structural plasticity]
GO:0051924 [regulation of calcium ion transport]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:0060998 [regulation of dendritic spine development]
GO:0061003 [positive regulation of dendritic spine morphogenesis]
GO:0090129 [positive regulation of synapse maturation]
GO:1900034 [regulation of cellular response to heat]
Show all
 492 aa
55.2 kDa 		No 1
CAMK2B-006
ENSP00000326427
ENST00000353625
Q13554 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0003779 [actin binding]
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007268 [synaptic transmission]
GO:0007411 [axon guidance]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010976 [positive regulation of neuron projection development]
GO:0014733 [regulation of skeletal muscle adaptation]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0030666 [endocytic vesicle membrane]
GO:0033017 [sarcoplasmic reticulum membrane]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042803 [protein homodimerization activity]
GO:0045087 [innate immune response]
GO:0046777 [protein autophosphorylation]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048169 [regulation of long-term neuronal synaptic plasticity]
GO:0051823 [regulation of synapse structural plasticity]
GO:0051924 [regulation of calcium ion transport]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:0060998 [regulation of dendritic spine development]
GO:0061003 [positive regulation of dendritic spine morphogenesis]
GO:0090129 [positive regulation of synapse maturation]
GO:1900034 [regulation of cellular response to heat]
Show all
 479 aa
54.1 kDa 		No 1
CAMK2B-007
ENSP00000326518
ENST00000346990
Q13554 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0003779 [actin binding]
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007268 [synaptic transmission]
GO:0007411 [axon guidance]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010976 [positive regulation of neuron projection development]
GO:0014733 [regulation of skeletal muscle adaptation]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0030666 [endocytic vesicle membrane]
GO:0033017 [sarcoplasmic reticulum membrane]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042803 [protein homodimerization activity]
GO:0045087 [innate immune response]
GO:0046777 [protein autophosphorylation]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048169 [regulation of long-term neuronal synaptic plasticity]
GO:0051823 [regulation of synapse structural plasticity]
GO:0051924 [regulation of calcium ion transport]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:0060998 [regulation of dendritic spine development]
GO:0061003 [positive regulation of dendritic spine morphogenesis]
GO:0090129 [positive regulation of synapse maturation]
GO:1900034 [regulation of cellular response to heat]
Show all
 449 aa
51 kDa 		No 1
CAMK2B-008
ENSP00000326375
ENST00000350811
Q13554 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0003779 [actin binding]
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007268 [synaptic transmission]
GO:0007411 [axon guidance]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010976 [positive regulation of neuron projection development]
GO:0014733 [regulation of skeletal muscle adaptation]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0030666 [endocytic vesicle membrane]
GO:0033017 [sarcoplasmic reticulum membrane]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042803 [protein homodimerization activity]
GO:0045087 [innate immune response]
GO:0046777 [protein autophosphorylation]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048169 [regulation of long-term neuronal synaptic plasticity]
GO:0051823 [regulation of synapse structural plasticity]
GO:0051924 [regulation of calcium ion transport]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:0060998 [regulation of dendritic spine development]
GO:0061003 [positive regulation of dendritic spine morphogenesis]
GO:0090129 [positive regulation of synapse maturation]
GO:1900034 [regulation of cellular response to heat]
Show all
 542 aa
60.4 kDa 		No 1
CAMK2B-015
ENSP00000400387
ENST00000424197
E9PBE8 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit beta
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 168 aa
19 kDa 		No 0
CAMK2B-016
ENSP00000390419
ENST00000415369
E7EQE4 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit beta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 173 aa
19.6 kDa 		No 0
CAMK2B-020
ENSP00000388445
ENST00000421607
E7ETC9 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit beta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 180 aa
20.5 kDa 		No 0
CAMK2B-021
ENSP00000388951
ENST00000433930
H7BZC6 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit beta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0005524 [ATP binding]
GO:0006468 [protein phosphorylation]
Show all
 184 aa
19.6 kDa 		No 0
CAMK2B-022
ENSP00000410445
ENST00000425809
H7C394 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit beta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005516 [calmodulin binding]
GO:0006468 [protein phosphorylation]
Show all
 184 aa
20.4 kDa 		No 0
CAMK2B-026
ENSP00000258682
ENST00000258682
Q13554 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0003779 [actin binding]
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007268 [synaptic transmission]
GO:0007411 [axon guidance]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010976 [positive regulation of neuron projection development]
GO:0014733 [regulation of skeletal muscle adaptation]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0030666 [endocytic vesicle membrane]
GO:0033017 [sarcoplasmic reticulum membrane]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042803 [protein homodimerization activity]
GO:0045087 [innate immune response]
GO:0046777 [protein autophosphorylation]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048169 [regulation of long-term neuronal synaptic plasticity]
GO:0051823 [regulation of synapse structural plasticity]
GO:0051924 [regulation of calcium ion transport]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:0060998 [regulation of dendritic spine development]
GO:0061003 [positive regulation of dendritic spine morphogenesis]
GO:0090129 [positive regulation of synapse maturation]
GO:1900034 [regulation of cellular response to heat]
Show all
 517 aa
57.9 kDa 		No 1
CAMK2B-201
ENSP00000390292
ENST00000457475
Q13554 [Direct mapping]
Calcium/calmodulin-dependent protein kinase type II subunit beta
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000165 [MAPK cascade]
GO:0000186 [activation of MAPKK activity]
GO:0003779 [actin binding]
GO:0004672 [protein kinase activity]
GO:0004683 [calmodulin-dependent protein kinase activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006468 [protein phosphorylation]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0007268 [synaptic transmission]
GO:0007411 [axon guidance]
GO:0008286 [insulin receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0010976 [positive regulation of neuron projection development]
GO:0014733 [regulation of skeletal muscle adaptation]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0030666 [endocytic vesicle membrane]
GO:0033017 [sarcoplasmic reticulum membrane]
GO:0034605 [cellular response to heat]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042803 [protein homodimerization activity]
GO:0045087 [innate immune response]
GO:0046777 [protein autophosphorylation]
GO:0048010 [vascular endothelial growth factor receptor signaling pathway]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048169 [regulation of long-term neuronal synaptic plasticity]
GO:0051823 [regulation of synapse structural plasticity]
GO:0051924 [regulation of calcium ion transport]
GO:0060333 [interferon-gamma-mediated signaling pathway]
GO:0060998 [regulation of dendritic spine development]
GO:0061003 [positive regulation of dendritic spine morphogenesis]
GO:0090129 [positive regulation of synapse maturation]
GO:1900034 [regulation of cellular response to heat]
Show all
 518 aa
58 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.