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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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RAB13
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

RAB13

Gene description

RAB13, member RAS oncogene family

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly not consistent with RNA expression data.

Reliability score

Approved based on 1 antibody.
HPA003996
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
N/A
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

RAB13

Synonyms

Description

RAB13, member RAS oncogene family (HGNC Symbol)

Entrez gene summary

This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12. [provided by RefSeq, Jan 2013]

Chromosome

1

Cytoband

q21.3

Chromosome location (bp)

153981617 - 153986358

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000143545 (version 83.38)

Entrez gene

5872

UniProt

P51153 (UniProt - Evidence at protein level)

neXtProt

NX_P51153

Antibodypedia

RAB13 antibodies

PROTEIN BROWSER

RAB13-001
RAB13-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RAB13-001
ENSP00000357564
ENST00000368575
P51153 [Direct mapping]
Ras-related protein Rab-13
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005923 [bicellular tight junction]
GO:0006886 [intracellular protein transport]
GO:0006913 [nucleocytoplasmic transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0010737 [protein kinase A signaling]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0016197 [endosomal transport]
GO:0016328 [lateral plasma membrane]
GO:0030027 [lamellipodium]
GO:0030139 [endocytic vesicle]
GO:0030658 [transport vesicle membrane]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0031175 [neuron projection development]
GO:0031410 [cytoplasmic vesicle]
GO:0032456 [endocytic recycling]
GO:0032482 [Rab protein signal transduction]
GO:0032593 [insulin-responsive compartment]
GO:0032869 [cellular response to insulin stimulus]
GO:0034236 [protein kinase A catalytic subunit binding]
GO:0035767 [endothelial cell chemotaxis]
GO:0043005 [neuron projection]
GO:0044795 [trans-Golgi network to recycling endosome transport]
GO:0055037 [recycling endosome]
GO:0055038 [recycling endosome membrane]
GO:0061024 [membrane organization]
GO:0070062 [extracellular exosome]
GO:0070830 [bicellular tight junction assembly]
GO:0072659 [protein localization to plasma membrane]
GO:0090002 [establishment of protein localization to plasma membrane]
GO:0097368 [establishment of Sertoli cell barrier]
GO:1902463 [protein localization to cell leading edge]
Show all
203 aa
22.8 kDa
No 0
RAB13-201
ENSP00000480103
ENST00000614713
A0A087WWB9 [Direct mapping]
Ras-related protein Rab-13
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0006886 [intracellular protein transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0030866 [cortical actin cytoskeleton organization]
GO:0032482 [Rab protein signal transduction]
Show all
122 aa
13.6 kDa
No 0

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