Tissue expression of ARMC10 - Summary - The Human Protein Atlas

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ARMC10

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TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ARMC10
Gene description	Armadillo repeat containing 10
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Granular cytoplasmic expression in most tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA011036 , HPA011057
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ARMC10 (HGNC Symbol)
Synonyms	MGC3195, SVH
Description	Armadillo repeat containing 10 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011]
Chromosome	7
Cytoband	q22.1
Chromosome location (bp)	103074881 - 103099764
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000170632 (version 83.38)
Entrez gene	83787
UniProt	Q8N2F6 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N2F6
Antibodypedia	ARMC10 antibodies

PROTEIN BROWSER

ARMC10-001	ARMC10-002	ARMC10-003	ARMC10-004	ARMC10-007	ARMC10-008	ARMC10-201	ARMC10-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARMC10-001 ENSP00000319412 ENST00000323716	Q8N2F6 [Direct mapping] Armadillo repeat-containing protein 10 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005739 [mitochondrion] GO:0005789 [endoplasmic reticulum membrane] GO:0016021 [integral component of membrane] GO:0040008 [regulation of growth] Show all	343 aa 37.5 kDa	No	1
ARMC10-002 ENSP00000396654 ENST00000428183	Q8N2F6 [Direct mapping] Armadillo repeat-containing protein 10 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005789 [endoplasmic reticulum membrane] GO:0016021 [integral component of membrane] GO:0040008 [regulation of growth] Show all	284 aa 31.1 kDa	No	1
ARMC10-003 ENSP00000413619 ENST00000441711	Q8N2F6 [Direct mapping] Armadillo repeat-containing protein 10 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005789 [endoplasmic reticulum membrane] GO:0016021 [integral component of membrane] GO:0040008 [regulation of growth] Show all	308 aa 33.8 kDa	No	1
ARMC10-004 ENSP00000405612 ENST00000454559	Q8N2F6 [Direct mapping] Armadillo repeat-containing protein 10 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005789 [endoplasmic reticulum membrane] GO:0016021 [integral component of membrane] GO:0040008 [regulation of growth] Show all	249 aa 27.4 kDa	No	1
ARMC10-007 ENSP00000398201 ENST00000434153	C9J5N7 [Direct mapping] Armadillo repeat-containing protein 10 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0016021 [integral component of membrane] Show all	233 aa 25.4 kDa	No	1
ARMC10-008 ENSP00000406840 ENST00000431642	H7C2M7 [Direct mapping] Armadillo repeat-containing protein 10 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] Show all	185 aa 20.6 kDa	No	0
ARMC10-201 ENSP00000397969 ENST00000425331	Q8N2F6 [Direct mapping] Armadillo repeat-containing protein 10 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005789 [endoplasmic reticulum membrane] GO:0016021 [integral component of membrane] GO:0040008 [regulation of growth] Show all	284 aa 31.2 kDa	No	1
ARMC10-202 ENSP00000440463 ENST00000541300	Q8N2F6 [Direct mapping] Armadillo repeat-containing protein 10 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005789 [endoplasmic reticulum membrane] GO:0016021 [integral component of membrane] GO:0040008 [regulation of growth] Show all	225 aa 24.8 kDa	No	1

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.