THE HUMAN PROTEIN ATLAS BLOG

Biomarker for prognosis in endometrial carcinoma

2016-03-01
ASRGL1 Cancer Endometrial Carcinoma Microarray Tissue Atlas

Reduced expression of ASRGL1 was significantly associated with poor prognosis and reduced disease-specific survival.

Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma

The ASRGL1 protein is a novel, powerful, and independent biomarker for prognosis in endometrial carcinoma.

In a recent study by scientists from the Human Protein Atlas project and collaborators at the University of Bergen and University of Turku, the l-asparaginase (ASRGL1) protein was identified as an endometrial carcinoma biomarker candidate by searches in the HPA-database.

ASRGL1 expression was immunohistochemically evaluated on two large independent endometrial carcinoma cohorts using an extensively validated antibody...Read more


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