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ETFB

GENERAL INFORMATION

Gene name

 ETFB

Gene description

 Electron-transfer-flavoprotein, beta polypeptide

Protein class

 Disease related genes
Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplasmic expression with a granular pattern.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data. External characterization data supports antibody staining.

Reliability score

 Supported based on 3 antibodies.
HPA018910 , HPA018921 , HPA018923
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Adrenal gland

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 ETFB

Synonyms

Description

 Electron-transfer-flavoprotein, beta polypeptide (HGNC Symbol)

Entrez gene summary

 This gene encodes electron-transfer-flavoprotein, beta polypeptide, which shuttles electrons between primary flavoprotein dehydrogenases involved in mitochondrial fatty acid and amino acid catabolism and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. The gene deficiencies have been implicated in type II glutaricaciduria. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 19

Cytoband

 q13.41

Chromosome location (bp)

 51345169 - 51366418

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000105379 (version 83.38)

Entrez gene

 2109

UniProt

 P38117 (UniProt - Evidence at protein level)

neXtProt

 NX_P38117

Antibodypedia

 ETFB antibodies

PROTEIN BROWSER
ETFB-001
ETFB-002
ETFB-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ETFB-001
ENSP00000311930
ENST00000309244
P38117 [Direct mapping]
Electron transfer flavoprotein subunit beta
Show all
Predicted intracellular proteins
Plasma proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005739 [mitochondrion]
GO:0005759 [mitochondrial matrix]
GO:0009055 [electron carrier activity]
GO:0022904 [respiratory electron transport chain]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0044237 [cellular metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0070062 [extracellular exosome]
Show all
 255 aa
27.8 kDa 		No 0
ETFB-002
ENSP00000346173
ENST00000354232
P38117 [Direct mapping]
Electron transfer flavoprotein subunit beta
Show all
Predicted intracellular proteins
Plasma proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005739 [mitochondrion]
GO:0005759 [mitochondrial matrix]
GO:0009055 [electron carrier activity]
GO:0022904 [respiratory electron transport chain]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0044237 [cellular metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0070062 [extracellular exosome]
Show all
 346 aa
37.4 kDa 		No 0
ETFB-004
ENSP00000469628
ENST00000596253
M0QY67 [Direct mapping]
Electron transfer flavoprotein subunit beta
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0009055 [electron carrier activity]
Show all
 178 aa
19.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.