THE HUMAN PROTEIN ATLAS BLOG

Ovarian Cancer Awareness Month

2017-09-29
Cancer Immunohistochemistry Life Science Ovarian cancer awareness Pathology Atlas Plasma Profilling TCGA tissue

Figure 1. Immunohistochemical staining of EPCAM using antibody CAB055098 shows differential expression, both high (left panel) and low (right panel) in samples from ovarian cancer patients.

In this week's Pathology Atlas blog post, we highlight genes with prognostic association to ovarian cancer , as September is National Ovarian Cancer Awareness Month in the US. Ovarian cancer is the fifth most frequent cause of cancer death in women, and 50% of all ovarian cancers are diagnosed in women older than 65 years of age.

Epithelial ovarian carcinoma is one of the most common gynecologic malignancy. There are five subtypes of epithelial ovarian carcinoma, of which high-grade serous carcinoma is the most common...Read more


Awareness for prostate cancer

2017-09-27
European Prostate Cancer Awareness Day Immunohistochemistry Life Science Pathology Atlas Prostate cancer Prostate Cancer Awareness Month TCGA tissue

Figure 1. Immunohistochemical staining of ODF2 using antibody HPA001874 shows differential expression in samples from prostate cancer patients.

As part of the release of the Pathology Atlas, the Human Protein Atlas Blog presents brief and informative summaries of most cancers, and highlight genes with prognostic association in the different cancer forms. The Pathology Atlas is an open access database which includes quantitative transcriptomics data and spatial proteomics data of the major human cancer types that have been analyzed using a systems level approach.

We focus on prostate cancer in this week's blog post to highlight Prostate Cancer Awareness Month in North America and the European Prostate Cancer Awareness Day on the 27th of September...Read more


Mathias Uhlen honored with the Swedish Research Award 2017

2017-09-21
Elixir Human Protein Atlas Life Science Precision medicin Precision medicine

Research!Sweden foundation

The Swedish Research Award 2017 has been awarded to Professor Mathias Uhlen by the foundation Research!Sweden. On the September 25th Mathias Uhlen will receive the award for research accomplishments regarding mapping of human proteins within the Human Protein Atlas. The mission of the Research!Sweden foundation is to raise awareness regarding the importance of medical research - for health and prosperity by honoring every year one researcher or politician with the award.

Anna Nilsson Vindefjärd general secretary of Research!Sweden motivates the nomination "Mathias Uhlén's research is extremely valuable both for today and future precision medicine...Read more


Human Protein Atlas presentations at the 16th HUPO World Congress

2017-09-14
Affinity proteomics Cell Atlas Conference Human Protein Atlas Immunofluorescence microscopy Immunohistochemistry Sub-cellular structures Tissue Atlas

Next week on the 17th to 21th of September, the human proteome organization (HUPO), is hosting the 16th HUPO World Congress in Dublin, Ireland. Several Human Protein Atlas-associated researchers will attend the meeting and represent the project in various sessions, including plenary and invited lectures, oral presentations and poster sessions.

HUPO is an international scientific organization representing and promoting proteomics through international cooperation and collaborations by fostering the development of new technologies, techniques and training...Read more


Symposium celebrating 100-years anniversary Knut and Alice Wallenberg foundation

2017-09-08
Cell Atlas Conference Human Protein Atlas Immunofluorescence microscopy Project Discovery Subcell Atlas subcellular structures

The Knut and Alice Wallenberg Foundation (KAW) cellebrates 100-years anniversary of funding research within natural sciences, technology and medicine. Since 1917, when KAW was established, grants have been awarded to enpower both scientific research and education beneficial for the society. Today the foundation is one of the largest private funders of scientific research in Europe.

The KAW funded Molecular Life Science - anniversary symposium is organised by the Royal Academy of Sciences together with KTH - The Royal Institute of Technology, Karolinska Institute and Stockholm University...Read more


Focusing on prognostic genes in breast cancer

2017-09-07
Breast Cancer Cancer Cancer Genome Atlas Immunohistochemistry Pathology Atlas TCGA tissue

Figure 1. Immunohistochemical staining of CBX3 using antibody HPA004902 shows a differential nuclear expression in samples from breast cancer patients.

The Pathology Atlas, recently published in Science presents key proteins associated with different cancer types. This week's news article will focus on breast cancer and proteins related to cancer prognosis.

Breast cancer is the most common invasive cancer form in women worldwide. The cancer can roughly be classified as ductal or lobular breast cancer depending on the origin. The majority of breast cancers develop sporadically, but for 5-10% of patients there is an inherited factor associated with increased breast cancer risk, namely the BRCA1 and BRCA2 genes. Women with abnormal BRCA1 or BRCA2 have higher risk of developing breast cancer...Read more


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