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84 GENES FOUND

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Gene

 

 

Gene description

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Protein class

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Tissue

Cell

Cancer

 

 

 

 

 

 

Subcellular location

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RNA tissue category

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PDGFRAPlatelet-derived growth factor receptor, alpha polypeptideCancer-related genes
CD markers
Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins
RAS pathway related proteins
Nucleus
Plasma membrane
Cell Junctions		Expressed in all
PHOX2BPaired-like homeobox 2bCancer-related genes
Disease related genes
Predicted intracellular proteins
Transcription factors
NucleoplasmTissue enriched
PMS1PMS1 homolog 1, mismatch repair system componentCancer-related genes
Predicted intracellular proteins
Nucleoplasm
Nuclear bodies		Expressed in all
PMS2PMS1 homolog 2, mismatch repair system componentCancer-related genes
Disease related genes
Predicted intracellular proteins
Nucleoplasm
Cytosol		Mixed
POLEPolymerase (DNA directed), epsilon, catalytic subunitCancer-related genes
Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Nucleus
Plasma membrane		Expressed in all
PRF1Perforin 1 (pore forming protein)Cancer-related genes
Disease related genes
Predicted secreted proteins
CytosolTissue enhanced
PRKAR1AProtein kinase, cAMP-dependent, regulatory, type I, alphaCancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
CytosolExpressed in all
PTCH1Patched 1Cancer-related genes
Disease related genes
Predicted intracellular proteins
Predicted membrane proteins
Golgi apparatusTissue enhanced
PTENPhosphatase and tensin homologCancer-related genes
Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Nucleoplasm
Cytosol		Mixed
RB1Retinoblastoma 1Cancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
NucleoplasmExpressed in all
RECQL4RecQ helicase-like 4Cancer-related genes
Predicted intracellular proteins
NucleusMixed
RETRet proto-oncogeneCancer-related genes
Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted membrane proteins
Predicted secreted proteins
Vesicles
Plasma membrane
Cytosol		Tissue enriched
SBDSShwachman-Bodian-Diamond syndromeCancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
Nucleus
Cytosol		Expressed in all
SDHAF2Succinate dehydrogenase complex assembly factor 2Cancer-related genes
Disease related genes
Predicted intracellular proteins
Predicted secreted proteins
Nucleoli
Mitochondria
Cytosol		Expressed in all
SDHBSuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)Cancer-related genes
Citric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Predicted secreted proteins
Nucleoplasm
Plasma membrane
Mitochondria		Expressed in all
SDHDSuccinate dehydrogenase complex, subunit D, integral membrane proteinCancer-related genes
Citric acid cycle related proteins
Disease related genes
FDA approved drug targets
Predicted membrane proteins
Predicted secreted proteins
Expressed in all
SETBP1SET binding protein 1Cancer-related genes
Disease related genes
Predicted intracellular proteins
Nucleus
Nuclear bodies
Cytosol		Expressed in all
SMAD4SMAD family member 4Cancer-related genes
Disease related genes
Predicted intracellular proteins
Transcription factors
Nucleoplasm
Centrosome
Cytosol		Expressed in all
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1Cancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
Nucleoplasm
Nucleoli fibrillar center		Expressed in all
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1Cancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
Transcription factors
NucleoplasmExpressed in all
STAT3Signal transducer and activator of transcription 3 (acute-phase response factor)Cancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
Transcription factors
Nucleoplasm
Cytosol		Expressed in all
STK11Serine/threonine kinase 11Cancer-related genes
Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Nucleoplasm
Cytosol		Expressed in all
SUFUSuppressor of fused homolog (Drosophila)Cancer-related genes
Disease related genes
Predicted intracellular proteins
NucleusMixed
TERTTelomerase reverse transcriptaseCancer-related genes
Disease related genes
Enzymes
Potential drug targets
Predicted membrane proteins
NucleoplasmNot detected
TP53Tumor protein p53Cancer-related genes
Disease related genes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Transcription factors
Transporters
NucleoplasmExpressed in all
TSC1Tuberous sclerosis 1Cancer-related genes
Disease related genes
Plasma proteins
Predicted membrane proteins
CytosolExpressed in all
TSC2Tuberous sclerosis 2Cancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
CytosolExpressed in all
TSHRThyroid stimulating hormone receptorCancer-related genes
Disease related genes
FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
Predicted secreted proteins
Tissue enriched
VHLVon Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligaseCancer-related genes
Disease related genes
Predicted intracellular proteins
Nucleoplasm
Cytosol		Expressed in all
WASWiskott-Aldrich syndromeCancer-related genes
Disease related genes
Predicted intracellular proteins
Tissue enhanced
WRNWerner syndrome, RecQ helicase-likeCancer-related genes
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Nuclear specklesMixed
WT1Wilms tumor 1Cancer-related genes
Disease related genes
Predicted intracellular proteins
Transcription factors
NucleoplasmTissue enhanced
XPAXeroderma pigmentosum, complementation group ACancer-related genes
Disease related genes
Predicted intracellular proteins
Nucleus
Cytokinetic bridge		Expressed in all
XPCXeroderma pigmentosum, complementation group CCancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
Nucleus
Plasma membrane		Expressed in all

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.