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835 GENES FOUND

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Gene

 

 

Gene description

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Protein class

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Tissue

Cell

Cancer

 

 

 

 

 

 

Subcellular location

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RNA tissue category

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INSRInsulin receptorCD markers
Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
RAS pathway related proteins
VesiclesExpressed in all
IRS1Insulin receptor substrate 1Disease related genes
Plasma proteins
Predicted intracellular proteins
Nucleoplasm
Cytosol		Mixed
INSInsulinCancer-related genes
Candidate cardiovascular disease genes
Disease related genes
Plasma proteins
Predicted secreted proteins
RAS pathway related proteins
Tissue enriched
IGF1RInsulin-like growth factor 1 receptorCancer-related genes
CD markers
Disease related genes
Enzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
RAS pathway related proteins
VesiclesMixed
IRS2Insulin receptor substrate 2Cancer-related genes
Plasma proteins
Predicted intracellular proteins
Aggresome
Cytosol		Mixed
IGF1Insulin-like growth factor 1 (somatomedin C)Cancer-related genes
Candidate cardiovascular disease genes
Disease related genes
Plasma proteins
Predicted secreted proteins
RAS pathway related proteins
Tissue enhanced
IGFBP3Insulin-like growth factor binding protein 3Cancer-related genes
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins
Nucleoplasm
Vesicles
Cytosol		Tissue enhanced
PIK3R1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha)Cancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
RAS pathway related proteins
CytosolExpressed in all
IDEInsulin-degrading enzymeEnzymes
FDA approved drug targets
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins
Expressed in all
IGF2Insulin-like growth factor 2Cancer-related genes
Disease related genes
Plasma proteins
Predicted membrane proteins
Predicted secreted proteins
Nucleoplasm
Vesicles		Tissue enriched
ABCC8ATP-binding cassette, sub-family C (CFTR/MRP), member 8Disease related genes
FDA approved drug targets
Plasma proteins
Predicted membrane proteins
Transporters
Nucleoli
Golgi apparatus
Cytosol		Tissue enhanced
IRS4Insulin receptor substrate 4Predicted secreted proteins
Tissue enhanced
GRB10Growth factor receptor-bound protein 10Cancer-related genes
Predicted intracellular proteins
Nuclear membrane
Vesicles		Expressed in all
INSRRInsulin receptor-related receptorEnzymes
Predicted membrane proteins
Tissue enhanced
PTPN1Protein tyrosine phosphatase, non-receptor type 1Enzymes
Predicted membrane proteins
Endoplasmic reticulumExpressed in all
IGFBP1Insulin-like growth factor binding protein 1Candidate cardiovascular disease genes
Plasma proteins
Predicted secreted proteins
Golgi apparatusGroup enriched
IGFBP4Insulin-like growth factor binding protein 4Plasma proteins
Predicted secreted proteins
Expressed in all
IGFBP5Insulin-like growth factor binding protein 5Plasma proteins
Predicted secreted proteins
VesiclesTissue enhanced
PDX1Pancreatic and duodenal homeobox 1Disease related genes
Predicted intracellular proteins
Transcription factors
NucleoplasmTissue enriched
SORBS1Sorbin and SH3 domain containing 1Predicted intracellular proteins
Plasma membrane
Focal adhesion sites
Centrosome		Expressed in all
IGFBP2Insulin-like growth factor binding protein 2, 36kDaCancer-related genes
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins
Endoplasmic reticulumExpressed in all
PRKCZProtein kinase C, zetaEnzymes
Plasma proteins
Predicted intracellular proteins
Plasma membrane
Cytosol		Tissue enhanced
PTPN11Protein tyrosine phosphatase, non-receptor type 11Cancer-related genes
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
RAS pathway related proteins
Nucleus
Nucleoli
Actin filaments
Cytosol		Expressed in all
AKT2V-akt murine thymoma viral oncogene homolog 2Cancer-related genes
Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
RAS pathway related proteins
Nucleus
Vesicles
Cytosol		Expressed in all
INSL3Insulin-like 3 (Leydig cell)Disease related genes
Predicted secreted proteins
Tissue enriched
INSL4Insulin-like 4 (placenta)Predicted secreted proteins
Tissue enriched
PHIPPleckstrin homology domain interacting proteinPredicted intracellular proteins
NucleoplasmExpressed in all
SHC1SHC (Src homology 2 domain containing) transforming protein 1Predicted intracellular proteins
RAS pathway related proteins
CytosolExpressed in all
SLC2A4Solute carrier family 2 (facilitated glucose transporter), member 4Disease related genes
Potential drug targets
Predicted membrane proteins
Transporters
Tissue enhanced
TSC2Tuberous sclerosis 2Cancer-related genes
Disease related genes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
CytosolExpressed in all
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1CD markers
Disease related genes
Enzymes
Potential drug targets
Predicted membrane proteins
Tissue enhanced
FFAR1Free fatty acid receptor 1FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
Tissue enhanced
GCKGlucokinase (hexokinase 4)Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Golgi apparatus
Cytosol		Mixed
GIPGastric inhibitory polypeptidePlasma proteins
Predicted secreted proteins
Group enriched
GPLD1Glycosylphosphatidylinositol specific phospholipase D1Enzymes
Plasma proteins
Predicted secreted proteins
Tissue enhanced
IGF2RInsulin-like growth factor 2 receptorCancer-related genes
CD markers
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Golgi apparatus
Vesicles		Expressed in all
INSIG2Insulin induced gene 2Predicted membrane proteins
Expressed in all
ISL1ISL LIM homeobox 1Predicted intracellular proteins
Transcription factors
NucleoplasmGroup enriched
KCNJ11Potassium channel, inwardly rectifying subfamily J, member 11Disease related genes
FDA approved drug targets
Predicted membrane proteins
Voltage-gated ion channels
Tissue enhanced
LEPLeptinCancer-related genes
Candidate cardiovascular disease genes
Disease related genes
Plasma proteins
Predicted secreted proteins
Tissue enriched
RPS6KB1Ribosomal protein S6 kinase, 70kDa, polypeptide 1Enzymes
Plasma proteins
Predicted intracellular proteins
NucleoplasmExpressed in all
SLC30A8Solute carrier family 30 (zinc transporter), member 8Predicted intracellular proteins
Predicted membrane proteins
Transporters
Tissue enhanced
SREBF1Sterol regulatory element binding transcription factor 1Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Transcription factors
Golgi apparatus
Cytosol		Expressed in all
IGFBP6Insulin-like growth factor binding protein 6Plasma proteins
Predicted secreted proteins
Tissue enhanced
INSIG1Insulin induced gene 1Plasma proteins
Predicted membrane proteins
VesiclesExpressed in all
INSL5Insulin-like 5Predicted secreted proteins
Group enriched
INSL6Insulin-like 6Predicted secreted proteins
Tissue enriched
PTPRNProtein tyrosine phosphatase, receptor type, NDisease related genes
Predicted intracellular proteins
Predicted membrane proteins
Endoplasmic reticulumTissue enriched
TBC1D4TBC1 domain family, member 4Disease related genes
Predicted intracellular proteins
CytosolExpressed in all
ADRA2AAdrenoceptor alpha 2AFDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
Mixed

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.