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30 GENES FOUND

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Gene

 

 

Gene description

x

 

 

Protein class

x

 

 

 

 

Tissue

Cell

Cancer

 

 

 

 

 

 

Subcellular location

x

RNA tissue category

x

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 
ACLYATP citrate lyaseCancer-related genes
Citric acid cycle related proteins
Enzymes
Plasma proteins
Predicted intracellular proteins
Nucleoplasm
Plasma membrane
Cytosol		Expressed in all
ACO1Aconitase 1, solubleCancer-related genes
Citric acid cycle related proteins
Enzymes
Plasma proteins
Predicted intracellular proteins
Mitochondria
Cytosol		Expressed in all
ACO2Aconitase 2, mitochondrialCitric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
MitochondriaExpressed in all
CSCitrate synthaseCitric acid cycle related proteins
Enzymes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
MitochondriaExpressed in all
DLATDihydrolipoamide S-acetyltransferaseCitric acid cycle related proteins
Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
MitochondriaExpressed in all
DLDDihydrolipoamide dehydrogenaseCitric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
MitochondriaExpressed in all
DLSTDihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)Citric acid cycle related proteins
Enzymes
Predicted intracellular proteins
Expressed in all
FHFumarate hydrataseCancer-related genes
Citric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
MitochondriaExpressed in all
IDH1Isocitrate dehydrogenase 1 (NADP+), solubleCancer-related genes
Citric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Nuclear bodies
Cytosol		Expressed in all
IDH2Isocitrate dehydrogenase 2 (NADP+), mitochondrialCancer-related genes
Citric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
MitochondriaExpressed in all
IDH3AIsocitrate dehydrogenase 3 (NAD+) alphaCitric acid cycle related proteins
Enzymes
Plasma proteins
Predicted intracellular proteins
MitochondriaExpressed in all
IDH3BIsocitrate dehydrogenase 3 (NAD+) betaCitric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
MitochondriaExpressed in all
IDH3GIsocitrate dehydrogenase 3 (NAD+) gammaCitric acid cycle related proteins
Enzymes
Plasma proteins
Predicted intracellular proteins
MitochondriaExpressed in all
MDH1Malate dehydrogenase 1, NAD (soluble)Cancer-related genes
Citric acid cycle related proteins
Enzymes
Plasma proteins
Predicted intracellular proteins
Centrosome
Cytosol		Expressed in all
MDH2Malate dehydrogenase 2, NAD (mitochondrial)Citric acid cycle related proteins
Enzymes
Plasma proteins
Predicted intracellular proteins
MitochondriaExpressed in all
OGDHOxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)Citric acid cycle related proteins
Enzymes
Plasma proteins
Predicted intracellular proteins
MitochondriaExpressed in all
OGDHLOxoglutarate dehydrogenase-likeCitric acid cycle related proteins
Predicted intracellular proteins
Nucleus
Nucleoli fibrillar center
Cytosol		Tissue enhanced
PCPyruvate carboxylaseCitric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
MitochondriaExpressed in all
PCK1Phosphoenolpyruvate carboxykinase 1 (soluble)Citric acid cycle related proteins
Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Tissue enhanced
PCK2Phosphoenolpyruvate carboxykinase 2 (mitochondrial)Citric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
MitochondriaGroup enriched
PDHA1Pyruvate dehydrogenase (lipoamide) alpha 1Citric acid cycle related proteins
Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Predicted secreted proteins
MitochondriaExpressed in all
PDHA2Pyruvate dehydrogenase (lipoamide) alpha 2Citric acid cycle related proteins
Enzymes
Predicted intracellular proteins
MitochondriaTissue enriched
PDHBPyruvate dehydrogenase (lipoamide) betaCitric acid cycle related proteins
Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins
Nucleoplasm
Mitochondria		Expressed in all
SDHASuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)Citric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
MitochondriaExpressed in all
SDHBSuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)Cancer-related genes
Citric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Predicted secreted proteins
Nucleoplasm
Plasma membrane
Mitochondria		Expressed in all
SDHCSuccinate dehydrogenase complex, subunit C, integral membrane protein, 15kDaCancer-related genes
Citric acid cycle related proteins
Disease related genes
Predicted intracellular proteins
Predicted membrane proteins
Expressed in all
SDHDSuccinate dehydrogenase complex, subunit D, integral membrane proteinCancer-related genes
Citric acid cycle related proteins
Disease related genes
FDA approved drug targets
Predicted membrane proteins
Predicted secreted proteins
Expressed in all
SUCLA2Succinate-CoA ligase, ADP-forming, beta subunitCitric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted intracellular proteins
MitochondriaExpressed in all
SUCLG1Succinate-CoA ligase, alpha subunitCitric acid cycle related proteins
Disease related genes
Enzymes
Plasma proteins
Potential drug targets
Predicted secreted proteins
Plasma membrane
Mitochondria		Expressed in all
SUCLG2Succinate-CoA ligase, GDP-forming, beta subunitCitric acid cycle related proteins
Enzymes
Plasma proteins
Predicted intracellular proteins
Plasma membrane
Mitochondria		Expressed in all

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.