Search: protein_class:7TM proteins predicted by MDM AND with_antibodies:Yes - The Human Protein Atlas

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552 GENES FOUND

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Gene

Gene description	x

Protein class	x

Tissue

Cell

Cancer

Subcellular location	x

RNA tissue category	x

LGR4

Leucine-rich repeat containing G protein-coupled receptor 4

Disease related genes
G-protein coupled receptors
Potential drug targets
Predicted membrane proteins
Predicted secreted proteins

Microtubule organizing center

Expressed in all

LGR5

Leucine-rich repeat containing G protein-coupled receptor 5

G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

LGR6

Leucine-rich repeat containing G protein-coupled receptor 6

G-protein coupled receptors
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins

Nucleoplasm
Plasma membrane

Tissue enhanced

Luteinizing hormone/choriogonadotropin receptor

Disease related genes
FDA approved drug targets
G-protein coupled receptors
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins

LMBR1 domain containing 1

Disease related genes
Potential drug targets
Predicted membrane proteins
Transporters

Expressed in all

Lysophosphatidic acid receptor 1

G-protein coupled receptors
Predicted membrane proteins

Nuclear speckles
Plasma membrane

Lysophosphatidic acid receptor 2

G-protein coupled receptors
Predicted intracellular proteins
Predicted membrane proteins
Transporters

Lysophosphatidic acid receptor 3

G-protein coupled receptors
Predicted membrane proteins

Plasma membrane

Tissue enhanced

Lysophosphatidic acid receptor 4

G-protein coupled receptors
Predicted intracellular proteins
Predicted membrane proteins
Transporters

Tissue enhanced

Lysophosphatidic acid receptor 5

G-protein coupled receptors
Predicted membrane proteins

Lysophosphatidic acid receptor 6

Disease related genes
G-protein coupled receptors
Potential drug targets
Predicted membrane proteins

Vesicles
Plasma membrane

Expressed in all

Leukotriene B4 receptor

G-protein coupled receptors
Predicted membrane proteins
Transporters

Tissue enhanced

Leukotriene B4 receptor 2

G-protein coupled receptors
Predicted membrane proteins

Nucleoplasm
Plasma membrane

Tissue enhanced

MAS1

MAS1 proto-oncogene, G protein-coupled receptor

Disease related genes
G-protein coupled receptors
Potential drug targets
Predicted membrane proteins

Tissue enhanced

MAS1 proto-oncogene like, G protein-coupled receptor

G-protein coupled receptors
Predicted membrane proteins

Nucleoplasm
Plasma membrane
Cytosol

Tissue enhanced

Membrane bound O-acyltransferase domain containing 1

Enzymes
Predicted membrane proteins

Membrane-bound transcription factor peptidase, site 2

Disease related genes
Enzymes
Potential drug targets
Predicted membrane proteins

Nucleoplasm
Mitochondria
Cytosol

Expressed in all

MC4R

Melanocortin 4 receptor

Disease related genes
G-protein coupled receptors
Potential drug targets
Predicted membrane proteins
Transporters

MC5R

Melanocortin 5 receptor

G-protein coupled receptors
Predicted membrane proteins

Tissue enriched

Major facilitator superfamily domain containing 10

Predicted membrane proteins

Nucleoplasm
Nuclear membrane

Expressed in all

Major facilitator superfamily domain containing 2A

Disease related genes
Potential drug targets
Predicted membrane proteins
Transporters

Plasma membrane
Cytosol
Cytoplasmic bodies

Tissue enhanced

MLC1

Megalencephalic leukoencephalopathy with subcortical cysts 1

Disease related genes
Potential drug targets
Predicted membrane proteins
Transporters

Tissue enriched

MMD

Monocyte to macrophage differentiation-associated

Predicted membrane proteins
Transporters

Tissue enhanced

Mannose-P-dolichol utilization defect 1

Disease related genes
Predicted intracellular proteins
Predicted membrane proteins

Endoplasmic reticulum
Mitochondria

Expressed in all

MAS-related GPR, member D

G-protein coupled receptors
Predicted membrane proteins

MAS-related GPR, member E

G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

MAS-related GPR, member F

G-protein coupled receptors
Predicted intracellular proteins
Predicted membrane proteins
Transporters

Nuclear membrane
Plasma membrane

MAS-related GPR, member G

G-protein coupled receptors
Predicted membrane proteins

Tissue enriched

MAS-related GPR, member X2

G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

Mitochondrially encoded cytochrome c oxidase III

Disease related genes
Potential drug targets
Predicted membrane proteins
Transporters

Expressed in all

Mitochondrially encoded NADH dehydrogenase 1

Disease related genes
Enzymes
Potential drug targets
Predicted membrane proteins

Expressed in all

Non imprinted in Prader-Willi/Angelman syndrome 1

Disease related genes
Potential drug targets
Predicted membrane proteins
Transporters

Tissue enhanced

NIPA-like domain containing 3

Predicted intracellular proteins
Predicted membrane proteins
Transporters

Expressed in all

NMBR

Neuromedin B receptor

G-protein coupled receptors
Plasma proteins
Predicted membrane proteins

Plasma membrane
Cytosol

Neuromedin U receptor 1

G-protein coupled receptors
Predicted membrane proteins
Transporters

Neuromedin U receptor 2

G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

NOX3

NADPH oxidase 3

Predicted membrane proteins
Transporters

NOX4

NADPH oxidase 4

Predicted membrane proteins
Transporters

Tissue enriched

Neuropeptide FF receptor 1

G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

Neuropeptide FF receptor 2

G-protein coupled receptors
Predicted membrane proteins
Predicted secreted proteins

Plasma membrane
Actin filaments

Tissue enhanced

Neuropeptide S receptor 1

Disease related genes
G-protein coupled receptors
Potential drug targets
Predicted membrane proteins

Neuropeptide Y receptor Y1

G-protein coupled receptors
Predicted intracellular proteins
Predicted membrane proteins

Nucleus
Mitochondria
Cytosol

Tissue enhanced

Neuropeptide Y receptor Y4

G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

Neurotensin receptor 1 (high affinity)

G-protein coupled receptors
Predicted membrane proteins
Transporters

Plasma membrane

Opsin 1 (cone pigments), short-wave-sensitive

Disease related genes
G-protein coupled receptors
Potential drug targets
Predicted membrane proteins

OPN3

G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

OPN5

G-protein coupled receptors
Predicted membrane proteins

Tissue enriched

Opioid receptor, delta 1

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

Opioid receptor, kappa 1

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Opioid receptor, mu 1

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Tissue enhanced

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.